New Study Links Oral Bacteria to Alzheimer’s Risk

New Study Links Oral Bacteria to Alzheimer’s Risk

Recent research has shed light on the intriguing connection between oral health and cognitive function, particularly in relation to Alzheimer’s disease. An investigation led by experts at the Pacific Neuroscience Institute and the University of Pennsylvania suggests that the bacteria present in our mouths could influence our risk of developing this debilitating condition.

The Study Background

Published in PNAS Nexus, this study analyzed mouth rinse samples from 110 participants aged over 50 in the UK. The subjects were divided into two groups: those showing no decline in brain function and those experiencing mild cognitive impairment, known to heighten the risk of Alzheimer’s.

Findings on Memory and Attention

The researchers made a significant discovery regarding the types of bacteria present in the subjects’ mouths. They found that higher concentrations of bacteria such as Neisseria and Haemophilus were associated with better memory, attention, and cognitive function.

Bacteria Linked to Memory Loss

Conversely, increased levels of Porphyromonas and Prevotella, often linked with periodontal disease, were correlated with memory issues and were commonly found in individuals having the APOE4 gene, a known Alzheimer’s risk factor.

Implications for Health

Previous studies have indicated a link between oral bacteria and dementia, suggesting that harmful bacteria may cause bodily inflammation that contributes to Alzheimer’s risk. The researchers theorize that some of these bacteria might enter the bloodstream, potentially harming the brain.

‘It is crucial not to jump to conclusions about cause and effect,’ says Dr. Mark Wolff from the University of Pennsylvania, emphasizing the need for cautious interpretation of these findings.

Improving Oral Health

To foster a healthier oral microbiome, a diet rich in vegetables, particularly those high in nitrate, is recommended by Dr. Jennifer Bramen. This may promote beneficial bacteria while suppressing those linked to cognitive decline.

Conclusion

This study highlights the importance of oral health in potentially mitigating risks associated with Alzheimer’s disease. While further research is required, adopting a healthier diet and maintaining oral hygiene could play vital roles in safeguarding brain health.